Chronobiology and chronotherapeutics applications to cardiovascular medicine

Chronobiology and chronotherapeutics. Applications to cardiovascular medicine.

The concept of homeostasis, ie, constancy of the milieu interne, has dominated the teaching, research, and practice of medicine during the 20th century. According to this theory, biologic functions and processes are maintained in relative constancy over time. The emerging concepts of chronobiology, the scientific discipline of biologic rhythm study, and the findings from research in this field ...

Chronobiology and chronotherapeutics.

Possible contribution of chronobiology to cardiovascular health

The daily variations found in many aspects of physiology are collectively known as circadian rhythm (from "circa" meaning "about" and "dien" meaning "day"). Circadian oscillation in clock gene expression can generate quantitative or functional variations of the molecules directly involved in many physiological functions. This paper reviews the molecular mechanisms of the circadian clock, the tr...

Hybrid Phantom Applications to Nuclear Medicine

Annually, many people are irradiated for diagnostic and therapeutic purposes. Assessment of radiation dose and its related risks to patients are important issues in radiation protection dosimetry. The complex mathematical calculations of the absorbed and effective doses are now done with computers. The calculations are performed with the help of anthropomorphic computational models of human bod...

Optimization of Perron eigenvectors and applications: from web ranking to chronotherapeutics

HAL is a multidisciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L'archive ouverte pluridisciplinaire HAL, est destinée au dépôt età la diffusion de documents scientifiques de niveau r...